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Your liver has enzymes called cytochrome p450- these are usually involved in metabolising drugs. They vary in a lot of people. Some people can have several copies of a gene for a particular enzyme, and others may lack one completely. Its possible you may lack an enzyme. A certain amount of people (I think its around 6-8% ) cant metabolise codeine. Codeine is turned into morphine in your liver at a level of about 10% if eaten, but has no effect of injected, as it has to be metabolised into morphine to have an effect. It has no effect on about 7% of people as they lack the enzyme. Conversely, if you drink grapefruit juice before you pop your codeine pill, the effects are greater, as it turns off the enzymes 'off switch'. A similar effect is thought to happen with consuming mango before you smoke weed. If it doesnt work for you, try another method. I find if I have an edible, I get either a slight 'not quite there' high, or else a very heavy stone. Good to take a tolerance break every once in a while. Your body tends to downregulate receptors if theres a lot of THC around.
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