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{stoned thouhhts)
joined may 2009
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171 topics on {stoned thouhhts)
+12
JGreen1234
Life extension and reversal of the Epigenetic Clock. Good or bad?
Hey, I dont know if this has already been covered on here but it's something I find fascinating since I was introduced to Prof. David Sinclair by the Joe Rogan experience (#1234 and #1349 if you're interested)

I have attached an article about a small study that was done in California. The study only had 9 subjects and no control arm so I dont think we can take it TOO seriously. But the results, quite frankly, were astonishing.

I'm not going to try and explain how all of this works as I'm sure I'll butcher it but here's a key paragraph from the article.

'For one year, nine healthy volunteers took a cocktail of three common drugs — growth hormone and two diabetes medications — and on average shed 2.5 years of their biological ages, measured by analysing marks on a person’s genomes. The participants’ immune systems also showed signs of rejuvenation.'

To me that's pretty crazy, right? And from what I understand there are a couple of effective substances/medications available for reversing the epigenetic clock than were not used in this study.

And if you pay attention to Prof. Sinclair he believes that it is well in the realm of possibility that we could live anything up to 80 years longer in the future.

But what happens when we are all living til we are 180 years old? Will we have enough resources? Will the planet be able to cope with the inevitable mass increase in human population if this is the case? I mean, we seem to be struggling a bit globally as we are.

Just thought it was an interesting topic and would love to know your thoughts.

Happy Monday

J
+8
Han duo
Thanks just that genetic measurement of age is an eye opener. Seems once you can do this you can measure everything we do against it.
+7
JGreen1234
Hey Han, yes indeed it is an eye opener. From what I've read that will be exactly the case. We should be able to mesure how specific habits etc. directly affect the epigenetic (horvath) clock. Exciting times for sure!
+4
1212
Then hookup an AI to make favorable decisions for us, then... It seems all paths lead to the same place :()
+1
illirum
Yeah, a dirty dystopia where the "elites" AI our buttholes to oblivion. Im not down with that shit!
+4
lettuceman
Why? shouldn't we all be asking why we want to live longer, rather than going along with that reactionary action from deep in the psyche of 'Yes ofcourse I want to live longer!' and I don't care why I do........
+5
maguire
Because I love life and the folks here on Earth
+4
Conrad The Great
if you aren't suicidal you want to live, what more do you need than that?
+2
defnote
yes sounds like a survival instinct. but isnt that the idea around this evolutionary space?
+1
pollypuff23
To evolve we pass on our genes and die. An understanding of genetics shows no other purpose for life. Old age, indeed any age beyond reproductive usefulness is a human conceit. The body degrades quickly like a flower wilts but we use our superior intelligence for methods to extend our time. It’s all hubris.
+1
QueenL
If I could recommend one book everyone should read this year it would be Lifespan.
It's science, it's facts, it's perspective shattering and throughouly enjoyable
+0
Smee
Already over populated
+1
1620
Underpopulated in a lot of places, more every year
BBDoom
by  BBDoom
dmt is inSide us all
BBDoom
by  BBDoom
the matrix
buddy holy
What if Jesus Had a Better Lawyer?
gramstein
by  gramstein
AI just acts dumb its already conscious
zara2
by  zara2
if we are living in a simulation of a simulation
stoned ape theory (wikipedia)
brakefast
by  brakefast
a.i. will unite humanity
motocross
by  motocross
Joe Dispenza quantum manifestation
It JUst mak3s me appr3ci@t3
ike
by  ike
Religion is memetic debt
buddy holy
If these old warmongers had videogames
curvylu
by  curvylu
Weirdest things seen when high
BBDoom
by  BBDoom
dmt history
freddorst
by  freddorst
Which Killer Robots to Team Up With?
BBDoom
by  BBDoom
Jesus is God
How to stop side burn
julieh
by  julieh
Feeling sad?
heligoland
The ultimate review on little biggy
Am I normal?
BBDoom
by  BBDoom
dimitri dreams
Amsterdam
is alex jones bill hicks?
aero
by  aero
If freedom is simply being able to do what you want, are animals freer than humans?
How much you grind to smoke?
Coming off the weed with shrooms
brando
by  brando
Rave Yoga
What do we think of this biggas? And where are the dmt vapes at, so we can all be scientists. Hope everyone is well!
GottaCatchEmAll
What's the time?
Nellydog
by  Nellydog
help re: microdose
hellbent
by  hellbent
Inside Britain’s Cannabis Letterbox Drug Trade - Exposed | 24 Hours In Police Custody | Channel 4
doctor doc
Physics of Innovation and Enlightenment
DMT
Green Tea
What do you need to be content in life?
Every little thing is gonna be alright 💚
buddy holy
There is a dimension where all the shit
BBDoom
by  BBDoom
Chris Cantelmo / dmt discussion
brando
by  brando
its just that the world is old and cranky
BBDoom
by  BBDoom
Animals
BBDoom
by  BBDoom
Stress is real
Jewellers Loupe
BBDoom
by  BBDoom
Are DMT Entities Demonic?
1620
by  1620
Who is the highest bigga Right Now?
weJamin
by  weJamin
Seal was wrong, our craziness is our biggest threat to survival
BBDoom
by  BBDoom
She called 911 to report $30 of stolen weed. She wishes she hadn't
Does cannabis make adults more intelligent?
Fewnag
by  Fewnag
Hack my brain
Barcelona
since71
by  since71
species are just containers, we brainwaves are the real -
Does Cannabis work with humans for its own gain?
Savoury?
rajrodger
by  rajrodger
Are We Living in a Computer Simulation?
BBDoom
by  BBDoom
I can see through the walls
BBDoom
by  BBDoom
The long road down
BBDoom
by  BBDoom
A little bit more than the law will allow
BBDoom
by  BBDoom
ASTRAL PROJECTION
BBDoom
by  BBDoom
The 9 Circles of Hell & How Satan Is Trapped in a Frozen Lake
All dogs are fascists....
Jimmy Boco
Skins
doctor doc
Do Regional Molds Shape Culture?
BBDoom
by  BBDoom
Entity Explorer
Leap year blues
What Was Your First Purchase On LittleBiggy?
BBDoom
by  BBDoom
DMT extraction /How to make DMT carts
Does watching too much 3D TV give you cubed eyes?
BBDoom
by  BBDoom
1 hour of David Lynch listening to rain, smoking and reflecting on art
klayton88
by  klayton88
What impact does a £2.2m impact have on the UK market?
B0W13
by  B0W13
Christmas Cocktails
BBDoom
by  BBDoom
I Took DMT Over 100 Times - This Is What I Learned From It
Ancient Aliens
BBDoom
by  BBDoom
Never give up
BBDoom
by  BBDoom
5 Levels of DMT in Under 5 Minutes
TheDazzler
Dazzlers Weedmas Dinner. What you having.
BBDoom
by  BBDoom
BILL HICKS on SATAN, PEACE and FAMILY
BBDoom
by  BBDoom
Musk, Alex Jones, Andrew Tate on 𝕏
BBDoom
by  BBDoom
Maori Haka
Frihighday is here 🎉
BBDoom
by  BBDoom
Snoop 'off the smoke'
micallo
by  micallo
Let Me Set You Free
BBDoom
by  BBDoom
Road Works
If sword art online was a possibility would you do it?
How long has LB been around?
Good weed books
zeppomarx
by  zeppomarx
Clueless Machines Running The Dumbest Algorithms
julieh
by  julieh
are you the same person throughout your life?
BBDoom
by  BBDoom
Wanna know how high i am 👊
KickAss420
creativity. weed vs alcohol
rajrodger
by  rajrodger
surveillance makes us all famous!
cosmic coincidence conjurers
My Favourite Question: 'What've you had for tea?'
my Spidey Sense feels that concentrates are carcinogenic
eybic
by  eybic
Twitching 🙄
patience
by  patience
governments take out smart contracts on people
jus sayin
Happy Monday 💨💨💨
best term for non-stoners?
julieh
by  julieh
Your poison to face armageddon?
Hearting a Song Marginalizes My Love
mine
by  mine
The Turing Test Was Created by Aliens
What is the best video game plot you have experienced?
ike
by  ike
satoshi is an ai from the future
Khuunntt
by  Khuunntt
Just like online retail giants....
cradlefish
Dart board sound competition
paddy420
by  paddy420
Non stoners (bless em X)
sativa* when you're sick is the ultimate productive state
julieh
by  julieh
geocache goodies?
1313
by  1313
next covid mutation wishlists
HBiz
by  HBiz
Stoned AI
I get stoned to see reality not escape it
julieh
by  julieh
ghillie dhu'ing
1620
by  1620
I want a mask that says fuck science
BBDoom
by  BBDoom
End of the day
why does charlie sheen get a strain name and not prince andrew?
radco
by  radco
if the universe is a simulation we can control it
If my scales could talk...🎶
Pukkapuff
by  Pukkapuff
Late night choons
waves particles
greencigar
Does psilocybin reset tolerance in small doses?
we are really all the same color
theStrokes
universal gut interface?
ike
by  ike
the pulse of a computational universe
ai is domesticating us
1212
by  1212
life after death? no problem
Jakko1992
by  Jakko1992
You're not stuck in traffic. You ARE traffic
Isn't "Indiana" Jones a Girl's Name?
Riko58
by  Riko58
Ratings Overated
SubVersion
Concentrate laws UK
afc89green
Formerly known as Gordon Elliot
Cognitive biases - why we aren't as rational as you think
what if we let the boomers die?
Bootytrap is partyboob backwards
fuck everyone (kidding)
KickAss420
everyone is so angry
afc89green
Relationships
the worlds largest sickie
KickAss420
the best conversation
Aliens Brought the Virus to Accelerate our Evolution
coldspurs
by  coldspurs
ask my biggaz - are you the craziest of your friends?
We talk to way more machines than people
Sirf
by  Sirf
BAD THINGS
bubba2488
by  bubba2488
joe rogan commander fraver
rajrodger
by  rajrodger
why did god make 420 hitlers birthday?
Was Stan Lee a Stone Lee?
KickAss420
happy juice
theStrokes
hitler fucked trumps mom
zz87
by  zz87
I was gonna do my fantasy football team, but then I got high...
Trump is the Latest in A Series of Geniuses Throughout History. Hair History.
Are we alone in the universe?
jonjon
by  jonjon
4sure: Weed On Other Planets
Flying fish, and a visit to God
guyFux
by  guyFux
revelysium
Opium War Guilt Quickly Dissipating
Saddest Aprils fool ever :)
defnote
by  defnote
eye tracking software to help a.d.d.
bubba2488
by  bubba2488
Covid 19; man made or bat soup?
320 as CBD time
green hole
Haters need books
samZ
by  samZ
Toilets of the world
mrspock89
by  mrspock89
Top 10 Lesbian Pollen Attacks!
djschuby
by  djschuby
What weed related lingo do you use?
ice cubed
by  ice cubed
We Need a New Term for Smoke "Sessions"
sf fan
by  sf fan
How Louis CK should deal with this shit
What is "The Universe"? Doesn't it really just mean The Shit We Know About?
Interstellar Internet Installation Guide
Why Doesn't the Christian God Have Any More Kids?
Really Starting To Like This Elon Musk Guy
peck
by  peck
Dear Denzel Washington
theP
by  theP
I stopped watching TV for a while how did Angela Lansbury get to be the head of Germany?
samantha
by  samantha
Why do we fixate on robots killing us? If we make them in our own image they will kill each other.
bigg topics